![]() Kettunen, H., Vuorenmaa, J., Valkonen, E. ![]() At: XIIIth International Symposium on Ruminant Physiology (ISRP 2019), Leipzig, Germany, 3-6 September 2019. (2019) Resin acid composition increases propionate and butyrate production in a Rumen Simulation Technique (RUSITEC) model. Kettunen, H., Frantzi, M., Vuorenmaa, J., Breves, G. ![]() At: The XIV th European Poultry Conference (EPC) 2014, Stavanger, Norway. (2014) A novel, resin-based dietary ingredient reduces the risk of necrotic enteritis in turkeys. Kettunen, H., Apajalahti, J., Valkonen, E., Rinttilä, T., Grönberg, H. At: XIII th International Symposium on Ruminant Physiology (ISRP 2019), Leipzig, Germany, 3-6 September 2019. (2019) The effects of in-feed resin acid inclusion on milk production responses of dairy cows. Kairenius, P., Mäntysaari, P., Lidauer P., Franco M., Frantzi, M., Kettunen H. At: 14th International Symposium on Digestive Physiology of Pigs, 21-24 August 2018, Brisbane, Australia. (2018) Late gestation diet supplementation of resin acid-enriched composition increases sow colostrum IgG, piglet colostrum intake and modulates sow gut microbiota. Hasan, S., Sani, S., Junnikkala, S., Orro, T., Peltoniemi, O., Oliviero, C. At: The 10 th European Symposium of Porcine Health Management (ESPHM) 2018, Barcelona, Spain. (2018) Dietary supplementation with tall oil fatty acid and resin acid increases sow colostrum IgG and piglets’ colostrum intake in free farrowing pen. Hasan, S., Saha, S., Yun, J., Peltoniemi, O. At: 3 rd International Symposium on Alternatives to Antibiotics (ATA) December 16-18, 2019, Bangkok, Thailand. (2019) Dietary resin acid supplementation improves the performance of sows and piglets. Hasah, S., Kamyzek, M., Vuorenmaa, J., Valkonen, E., and Kettunen, H. At: The 9 th European Symposium of Porcine Health Management (ESPHM) 2017, Prague, Czech Republic. (2017) Dietary supplementation of tall oil fatty acid and resin acid in farrowing sows can affect the colostrum quality. Hasan, S., Junnikkala, S., Peltoniemi, O. (2018) Tall oil fatty acid inclusion in the diet improves performance and increases ileal density of lactobacilli in broiler chickens. In: Journal of Applied Animal Nutrition 5: 1–5. (2018) In vitro inhibition studies of natural resin acids to Clostridium perfringens, Staphylococcus aureus and Escherichia coli O149. In: Journal of Applied Animal Nutrition 3: 1–9. (2015) Natural resin acid-enriched composition as a modulator of intestinal microbiota and performance enhancer in broiler chicken. Kettunen, H.,, Rinttilä, T., Grönberg, H., Valkonen, E. (2020) Effect of resin acid composition on growth performance, footpad dermatitis, slaughter value, and gastrointestinal tract development in turkeys. Lipiński, K., Vuorenmaa, J., Mazur-Kuśnirek, M. In: Journal of Applied Animal Nutrition 5: 1–8. (2017) Dietary resin acid composition as a performance enhancer for broiler chickens. Kettunen, H., van Eerden, E., Lipiński, K., Rinttilä, T., Valkonen, E. (2018) Late gestation diet supplementation of resin acid-enriched composition increases sow colostrum IgG content, piglet colostrum intake and modulates sow gut microbiota. Hasan, S., Saha, S., Junnikkala, S., Orro, T., Peltoniemi, O. (2020) Distribution, metabolism, and recovery of resin acids in the intestine and tissues of broiler chickens in a feeding trial with tall oil fatty acid-supplemented diets. In: Veterinary Research 50: 15.Īpajalahti, J., Vienola K., Raatikainen K., Kettunen H. (2019) In-feed resin acids reduce matrix metalloproteinase activity in the ileal mucosa of healthy broilers without inducing major effects on the gut microbiota. Progres® also beneficially modulates intestinal microbiota, favouring butyrate producers and lactobacilli, and reducing the growth of Gram-positive pathogens.Īguirre, M., Vuorenmaa, J., Kettunen, H., Valkonen, E., Callens, C., Haesebrouck, F., Ducatelle, R., Van Immerseel, F. Resin acids also reduce the number of inflammatory T-lymphocytes in the small-intestinal tissue.īy these mechanisms the resin acids of Progres® reduce the impact of inflammation to the epithelial integrity. Our research has demonstrated that diet-derived resin acids inhibit the expression and collagenolytic activity of inflammation-associated MMPs. This process damages epithelial integrity and leads to the “leaky gut syndrome”. Inflammation induces the expression of specific matrix metalloproteinase (MMP) enzymes which degrade collagen and other structural molecules of the extracellular matrix. Intestinal epithelium is composed by only one layer of cells which are attached to the collagen-rich basal membrane. ![]() Even subclinical inflammation impairs the epithelial barrier function and reduces the capacity for nutrient absorption. Intestinal epithelium is a crucially important tissue for high-performing farm animals. ![]()
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